News from the NNI Community - Research Advances Funded by Agencies Participating in the NNI

Researchers from the University of Wyoming, Pennsylvania State University, Northeastern University, the University of Texas at Austin, Colorado State University, and the National Institute for Materials Science in Tsukuba, Japan, have created an innovative method to control tiny magnetic states within ultrathin, two-dimensional (2D) van der Waals magnets – a process akin to how flipping a light switch controls a bulb. "Our research could lead to the development of novel computing devices that are faster, smaller and more energy-efficient and powerful than ever before,” said Jifa Tian, one of the scientists involved in this study. “Our research … sets the stage for new, powerful computing platforms, such as probabilistic computers.” 

Researchers from Rutgers University and Xi'an University of Architecture and Technology in China have found that people walking through a space where a consumer product containing nanoparticles was recently sprayed stirred residual specks off carpet fibers and floor surfaces, projecting them some three to five feet in the air. Gediminas Mainelis, the scientist who led this study, said that while it's still too early to gauge the long-term effects of these particles on people's health, the results are important to contemplate. "At this point, it's more about increasing awareness, so that people know just what they are using," he said.

Researchers from the University of Michigan, the University of California at Berkeley, Cornell University, the U.S. Department of Energy’s Argonne National Laboratory and Lawrence Berkeley National Laboratory (Berkeley Lab), and Dow Chemical have accomplished high-resolution, efficient 3D chemical imaging for the first time at the one-nanometer scale. Up to this point, nanomaterial researchers have had to choose between imaging 3D structure or 2D chemical distribution. This time, the researchers developed a process to collect 3D images at every tilt angle as well as chemical images every few tilts. A multi-modal algorithm then takes the information for both signal types and outputs the 3D structure and chemistry. This research work was done in part at the Molecular Foundry, a nanoscience user facility that is part of Berkeley Lab.

Researchers from the University of Wisconsin–Madison scientists, Northwestern University, Massachusetts General Hospital, and Grove Biopharma, Inc, in Chicago have developed a nanomaterial that could be an effective tool for treating Alzheimer’s and other neurodegenerative diseases. The nanomaterial, called a protein-like polymer, changed the interaction between two proteins that are believed to be involved in setting the stage for diseases like Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis. While the work was performed in cells in culture, the researchers are now taking it a step further in mouse models of neurodegenerative diseases.

Researchers from the University of Houston, Jackson State University, and Howard University have developed a new type of flexible high-energy-density capacitor, which is a device that stores energy. Although the prototype device is just 1-inch by 1-inch, scaled-up versions of this innovation could revolutionize energy storage systems across the medical, aviation, consumer electronics, and defense industries. The capacitor contains layered polymers with oriented 2D nanofillers made of mechanically exfoliated flakes of 2D materials. This new design showed improved performance with higher energy density and efficiency than capacitors with randomly blended-in nanofillers.  

In a first demonstration of "electron videography," researchers from the University of Illinois Urbana–Champaign and the Georgia Institute of Technology have captured a microscopic moving picture of the delicate dance between proteins and lipids found in cell membranes. The researchers achieved videography by combining a novel water-based transmission electron microscopy method with detailed, atom-level computational modeling. The water-based technique involves encapsulating nanometer-scale droplets in graphene so they can withstand the vacuum in which the microscope operates. "This is the first time we are looking at a protein on an individual scale and haven't frozen it or tagged it," said Aditi Das, one of the scientists involved in this study.

By analyzing the protein corona composition of gold nanoparticles, researchers from Michigan State University; the University of South Florida; Postnova Analytics Inc. in Salt Lake City, UT; and Clene Nanomedicine Inc. in Salt Lake City, UT, have explained how the protein corona helps to treat neurodegenerative diseases. The nanoparticles pass through the gastrointestinal tract and enter the body's circulatory system, where they interact with, and become coated by, blood proteins and other biomolecules. This forms the protein corona. "Our research shows that these gold nanocrystals, manufactured using a novel method to form specific structures and without surfactants, can form a distinct protein corona that facilitates access to brain tissue," says Morteza Mahmoudi, one of the scientists involved in this study.

By harnessing the weak van der Waals forces that bind layers of 2D materials together, researchers from Washington University in St. Louis; Ajou University in Suwon, South Korea; Chonnam National University in Gwangju, South Korea; and Sungkyunkwan University in Suwon, South Korea, have demonstrated a nondestructive method to comprehensively map the grain structure and crystal orientations of 2D materials. The key innovation lies in using a filter made from a single layer of high-quality, single-crystal graphene with a known orientation as a reference. An unknown sample is placed on top of this filter to create a temporary stack. By shining laser light on the stack and collecting the Raman signal, the researchers can map out the location and orientation of individual grains in the sample with sub-micron resolution. 

Electrostatic capacitors enable ultrafast charging and discharging, providing energy storage and power for smartphones, laptops, medical devices, and car electronics. But the ferroelectric materials used in these capacitors have significant energy loss, making it difficult to provide high energy storage capability. Now, researchers at Washington University in St. Louis; the Massachusetts Institute of Technology; Yonsei University in Seoul, South Korea; Sungkyunkwan University in Suwon, South Korea; Ulsan National Institute of Science and Technology in South Korea; and the Korea Institute of Science and Technology in Seoul have developed novel 2D/3D/2D heterostructures that can minimize energy loss while preserving the advantageous material properties of ferroelectric 3D materials. Their approach sandwiches 2D and 3D materials in atomically thin layers with carefully engineered chemical and nonchemical bonds between each layer. 

Researchers at the University of Illinois Urbana-Champaign, Seoul National University in South Korea, and the National Institute for Materials Science in Tsukuba, Japan, have developed a method to visualize the thermally induced rearrangement of two-dimensional (2D) materials, atom-by-atom, from twisted to aligned structures, using transmission electron microscopy. The researchers observed a new and unexpected mechanism for this rearrangement process. "People usually think of the two layers like having two sheets of paper twisted 45° to each other. To get the layers to go from twisted to aligned, you would just rotate the entire piece of paper," said Yichao Zhang, one of the scientists involved in this study. "But what we found, actually, is it has a nucleus – a localized nanoscale aligned domain – and this domain grows larger and larger in size.”